Actavis Daizepam

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diazepam together with opioids the dose and duration
of concomitant treatment should be limited by your
doctor.
Please tell your doctor about all opioid medicines
you are taking, and follow your doctor´s dose
recommendation closely. It could be helpful to inform
friends or relatives to be aware of the signs and
symptoms stated above. Contact your doctor when
experiencing such symptoms
• barbiturates such as phenobarbital (to treat epilepsy
and mental disorders)
Taking these medicines with diazepam could affect
your mental status, make you very sleepy and suppress
your breathing and blood pressure.
• disulfiram (to treat alcohol addiction). Taking this
medicine with diazepam could make you very sleepy
and can cause diazepam to be removed from the
body more slowly than usual.
• medicines for epilepsy e.g. phenytoin and
carbamazepine, as these can reduce the effect of
diazepam. Diazepam can furthermore affect how
phenytoin works.
• theophylline (to treat asthma and other breathing
disorders), as it can weaken the effect of diazepam.
• cimetidine, omeprazole or esomeprazole (stomach
acid reducing medicines), as these can cause
diazepam to be removed from the body more slowly
than usual.
• rifampicin (an antibiotic) as this can cause diazepam
to be removed from the body more quickly than
usual. The effect of diazepam can be weakened.
• atazanavir, ritonavir, delavirdine, efavirenz, indinavir,
nelfinavir or saquinavir (antivirals), fluconazole,
itraconazole, ketoconazole or voriconazole (antifungal medicines) as these can cause diazepam to be
removed from the body more slowly than usual and
therefore increase the risk of side effects.
• isoniazid (used to treat tuberculosis), as it can cause
diazepam to be removed from the body more slowly
than usual.
• oral contraceptives, as they can slow down the
removal of diazepam from the body and increase its
effect. Breakthrough bleeding can occur when taking
diazepam and oral contraceptives together, but the
contraceptive protection is not reduced.
• cisapride (used to treat stomach problems), as it can
cause diazepam to be removed from the body more
slowly than usual.
• corticosteroids (medicines used to treat inflammation
in the body) as they can weaken the effect of
diazepam.
• levodopa (used to treat Parkinson’s disease).
Diazepam can reduce the effect of levodopa.
• valproic acid (used to treat epilepsy and mental
disorders) as it can slow down the removal of
diazepam from the body and increase its effect.
• ketamine (an anaesthetic) as diazepam increases the
effect of ketamine.
Diazepam Actavis with food and drink
and alcohol
Do not drink alcohol while you are taking diazepam.
Alcohol may increase the sedative effects of Diazepam
Actavis and make you very sleepy.
You should not drink grapefruit juice while taking
diazepam as it causes diazepam to be removed from
the body more slowly and increases the risk of side
effects.
Pregnancy and breast-feeding
Ask your doctor or pharmacist for advice before taking
any medicine.
You should not take Diazepam Actavis if you are
pregnant, planning to become pregnant or are breastfeeding. If you take Diazepam Actavis late in pregnancy
or during labour your baby might have a low body
temperature, floppiness and breathing difficulties. If
taken regularly during late pregnancy, your baby may
develop withdrawal symptoms.
Driving and using machines
Diazepam Actavis may make you feel sleepy and
affect your concentration. It may also affect how your
muscles work. These effects may continue for several
days after discontinuation of treatment with diazepam.
Do not drive or use any tools or machines if you are
affected in this way.
Diazepam Actavis contains lactose
Diazepam Actavis contains lactose (a type of sugar).
If you have been told that you have intolerance to
some sugars contact your doctor before taking this
medicine.
3 How to take Diazepam Actavis
Always take this medicine exactly as your doctor
has told you. You should check with your doctor or
pharmacist if you are not sure.
Swallow the tablets with a glass of water.
[For 5 mg and 10 mg tablets:]
The tablets can be divided into equal halves.
Your doctor will decide the appropriate dose and
for how long you need to take the tablets. The usual
duration of treatment is not longer than 4 weeks. If
needed, your doctor might increase the duration of
treatment.
The usual doses:
Adults
For anxiety:
2-5 mg diazepam 2-3 times daily. The dose can
be increased up to a maximum of 30 mg daily in
2-4 divided doses.
For treatment of muscle spasm:
Up to 15 mg diazepam daily in 2-4 divided doses.
For treatment of muscle spasms in cerebral spasticity:
Up to a maximum of 60 mg daily in 3-4 divided doses

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